Learn more about cancer in the lymph nodes here. The report described supraclavicular lymph node swelling in an 11-year-old boy after receiving the human papillomavirus (HPV) vaccine. It’s important to note that preprint research has not gone through the formal peer review process.Ī 2019 case report suggested that lymphadenopathy may also be a temporary side effect of vaccines. Sometimes they can indicate a reaction to an infection.įor example, a preprint 2021 case study described a 12-year-old girl who developed supraclavicular lymphadenopathy due to COVID-19 infection. Swollen supraclavicular nodes are not always a sign of cancer. The Troisier sign can also occur due to other cancer types, including: VN enlargement is called the Troisier sign and can occur because of stage 4 gastrointestinal cancer. This is because lymphatic flow sends chest, abdomen, and pelvic drainage toward the supraclavicular lymph nodes on the left side of the body. If lymph node swelling occurs only on the left side, cancer is more likely in the abdomen or pelvis. Swollen supraclavicular nodes on either collarbone can indicate a chest malignancy, such as lung cancer. Usually, cancer has metastasized or progressed beyond the original cancer site.Īpproximately 34–50% of people with supraclavicular lymphadenopathy, the medical term for swollen supraclavicular lymph nodes, also have abdominal cancer. Swollen supraclavicular lymph nodes need a prompt evaluation since this type is associated with cancer. When a person is sick, the immune system produces more lymphocytes, which causes lymph nodes to swell.

Inside the lymph nodes are white blood cells called lymphocytes that destroy pathogens. The body’s cells and tissues eliminate waste using lymph fluid, which travels in vessels and passes through lymph nodes.

Lymph nodes are small glands that act as filters in the immune system.

Shotty lymph nodes may be reactive